Verbal Communication Essay Research Paper Child AbuseWhat free essay sample

Verbal Communication Essay, Research Paper Child Abuse What is child abuse? It is the physical or emotional maltreatment of a kid by a parent, guardian, or other individual. Reports of kid maltreatment, including sexual maltreatment, whipping, and slaying, have climbed in the United States and some governments believe that the figure of instances is mostly under reported. Child disregard is sometimes included in legal definitions of kid maltreatment to cover cases of malnutrition, abandonment, and unequal attention of a kid # 8217 ; s safety. When reported, kid maltreatment instances are complicated by unequal Foster attention services and a legal system that has problem suiting the suggestible nature of kids, who are frequently developmentally unable to separate fact from pretend ( Hay, 1996 ) . Many kids suffer at the custodies of grownups # 8211 ; frequently their ain parents. They are beaten, kicked, thrown into walls, and/or burned with coffin nails. They have their caputs held under the H2O of lavatory bowls, are scalded by hot H2O or they are forced to stand in stop deading showers until they pass out. We will write a custom essay sample on Verbal Communication Essay Research Paper Child AbuseWhat or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page A kid could be stuffed into running rinsing machines or sexually molested, suffer from disregard in the signifiers of famishment and deficiency of medical attending, and still travel unnoticed by foreigners. In fact, it is estimated that three kids die every twenty-four hours in the U.S. entirely from one signifier of kid maltreatment or another. It is a nauseating pattern that has no set criterion of regulations to complete off the persisting job. Different provinces have different methods and bureaus to assist forestall maltreatment in the place, some work rather good while others bomb # 8211 ; a unsafe gamble when it comes to the life or mental province of a kid. I have seen kid abuse first manus and up near. I serve on the Advisory Board and Board of Directors for Lutheran Social Services, Foster Care Division of Michigan. It is shocking, immoral and bosom wrenching to see how grownups can handle kids. The married woman and myself have fostered many kids. They have come out of some really dysfunctional places. Some of the kids we fostered have been sexually molested and severely abuse by their ain parents. What makes it so bad is that most of the kids think that this is acceptable behaviour and would travel back to their places if they could. We had one small male child who would instead eat out of the refuse than sit at the tabular array to eat. We fostered another household of two male childs and two misss. Their male parent and uncle had sexually abused them all. These kids ranged from 7 to 12 old ages of age. While these kids were populating with us, we had caught them several times commiting each other in a sexual mode. They thought thi s was normal and acceptable behaviour. I besides know of a batch of instances where kids even die at the custodies of their on parents. What has our society go? You find in a batch of instance where the culprit has been perpetrated. Approximately 1 in 6 male childs is sexually abused before the age of 16. Dr. William C. Holmes of the University of Pennsylvania School of Medicine said that when sexually abused male childs are non treated, society must subsequently cover with the ensuing jobs, including offenses, self-destruction, drug usage, and more sexual maltreatment. This rhythm must be broken. This job affects everyone. Most child maltreatment takes topographic point in the place and is started by individuals are know to and trusted by the kid. Even though it h as been widely publicized, maltreatment in day-care and foster-care scenes histories for merely a little figure of confirmed instances of kid maltreatment. In 1996, merely two per centum of all confirmed instances of kid maltreatment occurred in these scenes. Child abuse if 15 times more likely to happen in households where spousal maltreatment occurs. Children are three times more likely to be abused by their male parents than by their female parents. No differences have been found in the incidence of kid maltreatment in rural versus urban countries. Following are the types of maltreatment and the per centums of the different types. Neglect # 8211 ; 54 % Physical maltreatment # 8211 ; 25 % Sexual maltreatment # 8211 ; 11 % Emotional maltreatment # 8211 ; 3 % Other # 8211 ; 7 % ( Davis, 1998 ) . There are many parents that need aid in rearing. One of the ways to assist parents is to do certain their basic demands are met. Until parents # 8217 ; basic demands are met, they may happen it hard to run into the demands of their kids. The first thing parents need is aid in run intoing their basic demands for nutrient, shelter, vesture, safety and medical attention, reding and ECT. Merely when these demands are met can higher demands be addressed ( Rushton, 1997 ) . Another way8 to assist should be to place and handle parents who abuse intoxicant or drugs, and place and advocate parents who suffer from spousal maltreatment. Identifying and handling parents with psychologic jobs is besides of import. Other issues that need attending include fiscal concerns, and employment and legal jobs. Supplying an empathic ear and being a beginning of referral for aid with these issues may take doctors a long manner toward fostering destitute parents. The following higher degree of demand includ es instruction about clip direction and budgeting accomplishments, emphasis direction, get bying and rearing accomplishments such as appropriate subject, cognition of kid development, nutrition and eating jobs, and safety issues ( Rushton, 1997 ) . In my decision, many things need to go on at international, national, province and community degrees to forestall kid maltreatment. Surveies have shown that states with the most generous societal services have the lowest rate of kid homicide. Peoples should buttonhole for greater handiness of drug and intoxicant intervention plans, more shelters for the homeless, more accessible mental wellness attention and more shelters for abused adult females and kids. These plans and those that provide rearing accomplishments, support groups and reprieve attention for parents and attention givers should be available in every community. Child maltreatment is a complex job with many causes, it is of import that people non take a defeatist attitude toward its bar. Despite the absence of strong grounds to steer preventative attempts, society can make things to seek to forestall maltreatment. Showing increased concern for the parents or health professionals and increasing efforts to heighten their accomplishments as parents or attention givers may assist salvage the most vulnerable people, our kids, from the incubus of maltreatment and disregard. Plants Cited Hay, T. # 8220 ; Social Interventions to Prevent Child Abuse and Neglect. # 8221 ; Child Welfare 5 February 1996: 379-403. Rushton, Frank. # 8220 ; The Role of Health Care in Child Abuse and Neglect Prevention. # 8221 ; Pediatricss March 1997: 133-136. Davis, Laura. Stop Domestic Violence. New York: Macmillan, 1998.

t-box case study

t-box case study Faika Seda MORALIMBA- 2013310101641. Briefly explain how T-box revolutionizes the traditional product approach in the apparel industry. Do you think that this is a reasonable risk to take? Why? Why not?T-box was created by the top management team of Boyner Group in 2003. Boyner Group is the largest non-food retailer in Turkey since 1981. The group sells famous local and international brands of apparel, accessories, cosmetics and home appliances. Boyner Group targets middle-upper and upper income levels with a classic taste of fashion with high-class brands such as Network, Alt„Â ±ny„Â ±ld„Â ±z and Fabrika. In contrast with Boyner, T-box targets a younger market with a hip taste and a morbid sense of humor. T-box transforms textile products into fast moving consumer goods (FMCG), moving beyond the traditional understanding that clothes and accessories are rather in the shopping goods category. It became convenience good. Its target market volume is large, distribution i s very extensive.English: Logo of the clothing brand Cure ApparelPrices are not expensive.They wanted to create a new market and decided to treat the products under the clothing brand T-box as if they were Fast Moving Consumer Goods. Small packages which are fit in a hand, easy to carry especially for travel purposes, low priced products such as headbands, wallets, lighters and condoms at the cash desk has also allowed the brand to be perceived as "last minute, immediate purchase" brand and most importantly to support the FMCG image of the so-called fashion products, making them similar to the packaged fruit juices, toilet papers or house cleaning supplies lined up on a supermarket shelf.The approach to the design of packaging and the presentation of the packs at the point of purchase had a great effect on sales.The other step of revolution is that 1 euro/cent exists in the package of the...

Washington Irvings Famous Story of a Sleeping Man

Washington Irving's Famous Story of a Sleeping Man Rip van Winkle  is an 1819 story by Washington Irving, American short-story writer. The story was published as part of The Sketch Book of Geoffrey Crayon, and was based on a German fairy tale. It chronicles the story of a man who falls asleep in the Catskills just before the American Revolution, and wakes up 20 years later to a completely different society.   Rip ends up in the mountains in the first place while trying to escape his nagging wife, and meets a man struggling with a heavy keg of moonshine. He helps the man carry it to a hollow where they encounter strange men playing a game of ninepins. Rip drinks some of their moonshine, and falls asleep 20 years later with a rusted musket and a long beard. He later learns that the man with the keg was the ghost of Henry Hudson.   Here are some questions for study and discussion about Rip van Winkle: Who are the strange men that Rip encounters in the hollow? Is it helpful to know that the story is based on a German fairy tale? Why or why not? Is Rips long sleep a reward (perhaps for helping the men playing ninepins) or a punishment (for being a generally lazy guy)? What is the portrayal of women in the story, including that of Rips wife Dame van Winkle? Can you think of a more contemporary story where a nagging wife is so central to a storys plot? How does Irving reveal character in Rip van Winkle? Compare/Contrast Rip van Winkle with Gulliver of Gullivers Travels by Jonathan Swift. Are there other characters in literature that compare to Rip van Winkle? Is Rip van Winkle consistent in his actions? Is he a fully-developed character? Discuss some of the symbols in Rip Van Winkle. Compare Rip van Winkle  with The Legend of Sleepy Hollow. How are they similar? How are they different? How essential is the setting to the story? Could the story have taken place anywhere else? What if the story had been set before and after the Civil War, or the War of 1812? How realistic is Irvings depiction of the Catskills? Why did he choose to set the story there? How does time figure into the story? Why was Rips slumber 20 years long, and not 10 years or 30 years? What would a sequel to Rip van Winkle have looked like? What would you expect Rip would be doing in another 20 years time? Is Rip van Winkle a tragedy or a comedy? Is there a central moral or lesson to be learned? Is this a childrens story? Why or why not?

Individual Personal Reflection Paper Assignment Example | Topics and Well Written Essays - 500 words

Individual Personal Reflection Paper - Assignment Example ve learnt that Critical thinking, among other things, makes one think rationally and with more clarity irrespective of the field one is in; education, law, medicine, finance, or management. Critical thinking is a vital component as it enhances problem solving and proper thinking and can thus be termed as an asset. Secondly, it enables a person to have excellent communication skills. It improves language and comprehension abilities by aiding in the analysis of texts. Furthermore, critical thinking leads to self-reflection since we are able to reflect on our values and make proper decisions. With the changing, economic times which is driven by technology and information one needs to be able to effectively deal with these changes. This requires analysis of information thus pushing for intellectual skills, which we have learnt in this course. Since the start of this course, my critical thinking has vastly improved. It has helped me to think rationally and view things from a different perspective. I can now carefully reflect on my principles of reasoning and internalize them therefore, making me apply it in my day-to-day life. I am now in a position to expose fallacies and avoid faulty reasoning. I am able to come up with solutions to problems in a systematic way and prioritize ideas based on their importance. I have also been able to clearly come up with constructive arguments and evaluate them. More so, I am able to break down information into their constituent parts and logically understand the connections, relevance, and importance of these ideas. In the beginning, I was at the stage of unreflective thinker where I was unaware of significant problems in thinking, but so far I have advanced and I am now in the practicing thinker level. I feel I am at this level since I have recognized the need for regular practice in thinking. I am in a better position to solve problems by using the information that I have. However, limited it may be and to further deduce probable

Understanding the Motives and the Causes of Impulses Into Research Paper

Understanding the Motives and the Causes of Impulses Into International Relationships - Research Paper Example In the process of sharing these common resources and with the self-satisfaction tendency of individuals, there is need to put up mechanism to regulate self-centeredness of each individuals and to ensure that natural human rights – right to liberty, to life and to property – do not conflict with the similar rights for others in the same society. This mechanism is what constitutes politics and when it succeeds in its quest to preserve the natural rights of individuals under it while maintaining peaceful coexistence, then we may say that it is a legitimate political authority. Because the public is vulnerable to perpetuating individual interests, which may infringe into the rights of others, the conception of political legitimacy so that it fulfils its obligations cannot be left to the public. On this account, the legitimate political authority can be entrusted into the hands of philosophers who have the mental ability to conceive the best political order. Legitimacy in po litics qualifies the virtue of political institutions and political decisions on laws and policies. Philosophers are believed possess to the highest understanding of principles of nature and can be trusted to concoct the best political order. The philosophers’ in-depth analysis of concepts can evaluate the validity of claims and general discourse. With the limitation of human beings in terms of thinking and diversity in understanding and conception of ideas, philosophers too face the greatest threat of conceiving illegitimate and unethical political systems.

Anti-cancer Drug Targeting AFR Receptor

Anti-cancer Drug Targeting AFR Receptor Results 1a 1b Figure 1 Cell viability data based on the use of the XTT assay Two different lung tumor cell lines were tested: one expressing the mutated AFR receptor (blue line) and one that expresses wild-type AFR (orange line). Figure 1a represented AFR lung cancer cell line with Drug X and figure1b represented AFR lung cancer cell line with drug Y. Cells were seeded in wells of a 96 well plate at 3 x 10*4 cells/well before treatment with the drugs at the indicated concentrations for 72 hours (triplicate samples at each concentration). XTT assay reagent was then added to the wells and the absorbance measured at 450 nm. Control wells (no cells) contained medium but no cells. The Cell Proliferation XTT assay is a colorimetric assay for the nonradioactive analysis of cellular proliferation, viability, quantification of cytotoxic and cytostatic compounds like anticancer drugs and pharmaceutical compounds, evaluation of growth-inhibitory antibodies and physiological mediators that able to inhibit cell growth (Sigma-Aldrich, 2016). Sample is adherent or suspension which cultured in 96-well microplates. A fictional receptor (AFR) was targeted by anti-cancer drug to inhibit the mutated AFR function, causing an anti-proliferative effect and even cell death. XTT ((2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide)) assay was used to measure cell viability in the two different lung tumor cell lines, one expressing the mutated AFR receptor (AFR mut) and one that expresses wild-type AFR (AFR wt). Drug Y was observed to hinder cancer cell growth dose dependently (Figure 1). The amount of observed absorbance increases with cell number and incuba tion time for 72hours when a maximum absorbance level is reached. The plot of the XTT assay data should create a curve with a linear part. This area exhibits the highest sensitivity to changes produced by the experimental parameters. Establishing the XTT assay data for treatment of AFR mutated and AFR wild-type lung cancer cell line with drug X from 0nm to 1600nm (Figure 1a), It was illustrated that the cell viability of mutated AFR increased considerably from 1.1 to 1.3 between 0nm and 800nm and then became steady at approximately 1.4 from 800nm to 1600nm. Compared with the wild type of AFR (Figure1a), the trend of the line was similar to the mutated one but the cell viability was first rised from 0.9 to 1.2 between 0nm and 800nm and finally exhibited a loss of linearity when greater than 800nm. The lung cancer cell line with drug X represented a cell proliferation assay because the absorbance values of the mutated one were greater than control conditions, representing an increase in cell proliferation and viability. On the other hand, investigating the XTT assay data for treatment of AFR mutated and AFR wild-type lung cancer cell line with drug Y from 0nm to 1600nm, It was indicated that the cell viability of m utated AFR started off at about 1.1 from 0nm to 50nm and then occurred a dramatic drop from 1.1 to 0.1 between 50nm to 400nm and finally lied on 0.03 at 1600nm (Figure1b). Compared with the wild type of AFR (Figure1b), the line was also decreasing but showed a completely different trend. The cell viability decreased from 0.89 to 0.88 between 0nm and 800nm stably and then exhibited a significant drop when greater than 800nm and finally lied on 0.8 of 1600nm. The lung cancer cell line with drug Y represented a cell apoptosis assay as the absorbance values were lower than control conditions, showing a decrease in cell proliferation and resulted from cellular necrosis or apoptosis. From the data analysis, drug Y was successfully tested to inhibit the function of mutated AFR which have an anti-proliferative effect to cause cell death and drug Y could be put forward for further testing. Figure 2 Flow cytometry apoptosis data: Annexin V -FITC (x axis) and propidium iodide (Y axis)   Ã‚   The proapoptotic effect of drug X and Y. The AFRmut cell line was treated with each drug at a concentration of 800 nM for 24 hours. The cells were harvested, resuspended in buffer and then treated with Annexin V-FITC and propidium iodide. Cytograms of annexin-V-FITC binding against PI uptake show three populations: (i) viable cells (low FITC and low PI signal) in gate Lower Left; (ii) early apoptotic cells (high FITC and low PI signal) in gate Lower Right and (iii) cells that lost membrane integrity which results in late apoptosis (high FITC and high PI signal) in gate Upper Right. The percentage of cell death increases in the tumor cancer cell line of drug Y, as demonstrated by incorporation of Annexin V. The inhibition of cell proliferation caused by AFRmut was related to the apoptosis induction. Apoptosis is programmed as cell death which is important in development, in normal function of certain tissues and in the response to the damage. Apoptosis involves events which results in the destruction of cell. Annexin V -FITC is a protein that binds to phosphotidylserine which can be labelled and used to detect apoptotic cells. The flow cytometry apoptosis data was plotted on a dot plot and the lower left was represented the viable cells while the upper right and the lower right were represented the dead cells and the apoptotic cells respectively. From the apoptosis data (Figure2), it was observed that the untreated condition showed 77% viable cells and 21% of apoptotic effect. When AFRmut was treated with drug X, the viable cells were increased by 19% and the apoptotic effect was largely decreased to 3%. In contrast, the incorporation with drug Y lead to considerable anti-proliferative effect where 58% of apoptotic cells were observed and viable cells only remained as 40%. Related to the induction of programmed cell death, the majority of cells from the two tumor cell lines were alive upon carrier treatment, the use of AFRmut lead to the entrance of these cells into apoptosis with incorporation of Annexin V. The treatment of drug Y showed a significant apoptotic effect than the drug X, which has a potential to inhibit the function of mutated AFR and results in anti-proliferative effect. Figure 3 Flow cytometry cell cycle data: x-axis shows propidium iodide fluorescence and y-axis shows the number of cells The AFRmut cell line was treated with drug X and Y at a concentration of 800 nM for 24 hours and then fixed with ethanol and stained with propidium iodide before analysis in a flow cytometer. Treating with drug Y showed no cells in G2/M phase. The inhibition of cell proliferation induced by AFRmut was correlated with cell cycle which was evaluated with propidium iodide by flow cytometry. Cell cycle demonstrated the cell progression through a division cycle which result in cell growth and separation into two daughter cells. Live cell observation of cellular DNA and distribution of cell cycle are valuable to regulate apoptosis, and also the tumor behavior and suppressor gene systems. Cells would be distributed into three phases of cell cycle: G0 /G1 phase (2N), S phase (DNA synthesis with various DNA), and G2 /M phase (4N) to identify apoptotic cells with partial DNA content desirably   (Krishnakumar R, Kraus W ,2010). Propidium iodide fluorescence was needed in these actions to bind DNA. From the flow cytometry results by histogram (figure 3), the untreated condition showed 42% of cells in G0/G1 phase while 31% in S phase and 27% in G2/M phase. When the AFRmut was treated with drug X, the cell number in G1 phase dropped by 7% while there was increase of 6% in S Phase. DNA replication occurs more effectively during S phase. Tumor cells with a higher proportion of cells in S phase as tumors were growed faster and more aggressive in that phase so drug X induced proliferation of mutated AFR. However, the addition of drug Y caused effective anti-proliferation effect by increasing the cell numbers in G1 phase from 42% to 86% since the cell has left the cycle and has stopped dividing. There was increase in the cell numbers and grow in size. The decrease from 31% to 14% for S phase indicated the ineffective DNA replication. Moreover, there was no cells observed in G2/M phase when treated with drug Y which represented the increasing numbers of apoptotic cells and the G2/M pha se arrest, which failed the mitosis progression. Discussion Drug Y can be an effective anticancer drug which targets mutated AFR and inhibit its function to lead an anti-proliferative effect. In the present study, two lung tumor cell lines, mutated AFR receptor (AFRmut) and wild-type AFR (AFRwt), Drug Y was found that it could inhibit the growth of the AFR in vitro. The IC50 values of AFRmut and AFRwt were with the same range of 450nm. Additionally, the cell cycle revealed that Drug Y arrested mutated AFR at S phase and G2/M phase. Furthermore, the data demonstrated that Drug Y induced apoptosis in the mechanism assessed by 3 different methods: cell viability assay, apoptosis assay and the cell cycle of flow cytometry. Taken together, these results suggest that the inhibitory effect of Drug Y on cell proliferation in mutated AFR is mediated through induction of cell cycle arrest and apoptotic cell death. The limitation is the flow cytometry are only authorize the relative abundances of cell cycle phases compared to another (Dick FA, Dyson NJ, 2002). These actions can be examined by evaluating a coordinate sample of cells with mitotic inhibitor like nocodazole or G1/S inhibitor like aphidicolin. As these drugs establish a prevalent arrest in M-phase or early S-phase accordingly, moderately proliferating cells will gather at the drug inferred arrest location. For instance, cells arrested in G1 BY pRB expression will stay in G1 phase regardless of nocodazole treatment even regulating cells will accumulate in M-phase[13] Overall, the data demonstrated drug Y is able to develop an anti-cancer drug that targets a receptor called AFR (A Fictional Receptor) to block its activity. Drug Y successfully inhibits the function of mutated AFR by evaluating the cell viability assay, apoptosis assay and the cell cycle of flow cytometry. The assays showed an anti-proliferative effect and even cause cell death, which explains its significant antitumor activity in the various experimental investigations that have assessed. Thus, further studies about the way of administration, dose limiting toxicities and recommended doses are needed for the preclinical development of drug Y to evaluate the potential of the compound as an anticancer drug. References Dick FA, Dyson NJ, 2002. Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins. J. Virol.2;76: 6224-6224. Krishnakumar R, Kraus W, 2010. The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol Cell. 39:8-24 Matthew J., et al, 2012. Analysis of Cell Cycle Position in Mammalian Cells  (59): 3491. Sigma-aldrich, 2016. Cell Proliferation Kit II (XTT) [online] Available at: http://www.sigmaaldrich.com/catalog/product/roche/11465015001?lang=enregion=GB Wang, G., et al, 2005. Antitumor effect of ÃŽÂ ²-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death. Cellular and Molecular Life Sciences CMLS 62.7-8: 881-893.

Effects of electronic gadgets to students studying habits Essay

Abstract Almost all of the students especially high school students are seen of using different kinds of electronic gadgets everyday. Like cellphone, iPad, psp, etc. With that case, students who are addicted in using electronic gadgets affects their studies. As what I have observed, using of electronic gadgets gives bad effects to almost all of the students. The purpose of doing this study is to *Explain the disadvantages of using electronic gadgets among us students *Determine the positive and negative effects of Electronic gadget to students *Show the consequences of excessive use of Electronic gadgets to students *Give the students an advice on how to control their use of electronic gadget. To accomplish this study, I researched for some information that can help me to prove the content of my study. And to be able to solve this problem, I researched for some solutions that can help me to solve this kind of situation, which may also help me to show the goal of my study to my co-students who are addicted in using electronic gadgets. In that way, I can help to prevent the addiction of every student from electronic gadgets. Effects of electronic gadgets 3 EFFECTS OF ELECTRONIC GADGETS TO STUDENTS STUDYING HABITS â€Å"Modern technologies like television and computers provide identifiable educational advantages, such as greater access to information and more compelling presentations of that information. Over-use of technology, though, especially such gadgets as cell phones, iPods and video games.