Tuesday, August 25, 2020

Effect of Country Development on Technology

Impact of Country Development on Technology Presentation Innovation is getting progressively essential to the achievement of all business firms, and to the national financial development. The procedure of globalization is driven by innovation advancement and the capacity of companies to inspire the utilization of innovation adequately and quickly. The innovative hole between created nations and developing countries has limited yet at the same time stays gigantic. The initial step to narrowing the hole is for developing countries to ingest innovation effectively. The quick monetary development accomplished by the recently industrialized economies has created an immense measure of examination on the system behind the financial take off. As indicated by F. Montes-Negret (2008), progress in creating nations mirrors the ingestion of prior advancements not at the outskirts innovations. By and large terms, make up for lost time alludes to the capacity of a nation to lessen the hole in efficiency and pay as for the main global nations (Fagerberg-G odinho,2005). Perez (1988) sees getting up to speed as an issue of relative speed in a race along a fixed track, as indicated by him, innovation is comprehended to be a unidirectional procedure. Moreover, he sees that each nation is a fledgling as far as the recently rising techno-monetary worldview, which suggests the chance of being a tenderfoot. Exploration has shown that in the getting up to speed process, the newbie doesn't just follow the way of a mechanical improvement of the propelled nations. Rather, they would prefer to avoid a few phases or even make their own individual ways which are not the same as the created nations. By doing this, it might bring about the creating nations turning out to be mavericks in innovation progressing. For the nation to have development in economy and modern turn of events, it needs to have an absorptive limit and capacity to tap on the planets innovation pool. Cohen and Levinthal (2000) clarifies absorptive limit as the capacity to evaluate the estimation of outer information and innovation and to make vital speculations and changes to assimilate and apply these adjustments in a profitable way. The advancement of new-to-the world information can be viewed as inventive which can be an expensive learning action that a nation can utilize so as to find others through innovation ingestion. Development and innovation retention are two particular procedures, that is, advancement advances absorptive limit on the grounds that the age of human capital and new thoughts, and the related information overflow impacts, help assemble absorptive limit. RD is a key contribution to development and is additionally a contribution to retention limit. Assimilation of innovation is viewed as an important advance to advance the improvement of human capital and the profitable base, making ready for developments at the worldwide information wilderness. Innovative work (RD), licenses, exchange, and remote direct venture are significant channels of mechanical ingestion, permitting dissemination of new thoughts and assembling best practices among nations and firms. R D is a key contribution to development and is viewed as a significant key in the retention of innovation (Cohen and Levinthal). Rogers (2003) characterizes instances of innovation ingestion as the appropriation of new item and assembling forms created in different nations; redesigning of an old item or procedure, permitting innovation, improving hierarchical proficiency and accomplishing quality accreditation. This paper will examine how appropriately planned financial approaches can altogether impact how much a nation assimilates new innovation, that is, it will talk about the pre necessities for innovation get ups. The requirement for a steady and helpful strategy structure and a business-accommodating venture atmosphere is the thing that makes the countrys capacity to retain innovation and information, and this relies upon its association and the aptitudes of its workforce. Further more the paper will talk about the channels that creating nations can use to find other created nations through innovation assimilation, for example, exchange streams, remote direct venture (FDI), RD and licenses. Writing Review The rich writing on make up for lost time through innovation is loaded with nations that in the previous decades have overseen find the created nations, others that have prevailing ahead and a few that have fallen behind in innovation and neglected to be standard with the created world (Abramovitz, 1986). More exploration has distinguished a progression of components that have influenced the wellsprings of make up for lost time. One of the components is respect to the nearness of learning and capacities in the local firms (Bell and Pavitt, 1993, Kim, 1997; 1999, Lall, 2001, Kim and Nelson, 2000, Lee, 2005). Make up for lost time nations should attempt to embrace the Schumpeterian perspective on the procedure of development, as indicated by which financial operators are probably going to enhance as a response to startling changes inside the monetary condition (Schumpeter, 1947). From the early conventional writing that underlined how it was conceivable to close the hole however move o f innovation and the impersonation of effectively accessible innovation, the writing on abilities has mightily moved to show the focal job of the procedure of capacity gathering by local firms and the need of different kinds of capacities for make up for lost time: absorptive capacities, advancement capacities and reciprocal resources so as to receive, adjust and alter advances grew somewhere else or in the end create new ones. As a matter of fact, the most flow research has demonstrated that any procedure of improvement and development suggests an advancement, and that successions of steps in the ability building process are important for advancement. The writing has likewise focused on the job of social capacities (Abramovitz 1986) and the expansive establishments of a nation, including the examination foundation (Mazzoleni and Nelson,2006) and budgetary organizations (Gerschenkron, 1962). In the getting up to speed in pay per capita or efficiency open arrangement has frequently assumed a significant job in various manners and structures in a few nations, for example, Japan (Johnson,1982), Korea (Kim 1997), Taiwan (Wade, 1990) and Brazil (Mani, 2004). Additionally the overhauling of the degree of human capital has demonstrated a key component for getting up to speed (Fagerberg and Godinho,2004 and Bernardes and Albuquerque, 2003). The writing further shows how innovation in development is the missing connection between the created and the less evolved nations. There is a chance of a make up for lost time situation if less created nations can access and utilize created innovation. At the end of the day, less created nations would develop at a higher rate until at such time that the contrasts among created and less created nations are irrelevant. This can be appeared by the experience of East Asian nations (World Bank, 1993). Getting up to speed is typically thought to be reliant fair and square of human capital and information. Capital is a fundamental instrument for the financial achievement on the planet today, in light of the fact that the countires need the ability to activate information and to utilize it without limit. An examination by the World bank (2009) demonstrates that nations in the Sub Sahara of Africa (SSA) must saddle both increasingly capital and more information. These African nations needs to put vigorously in physical foundation and profitable limit. Nonetheless, amplifying profitability and accomplishing intensity will rely on achievement in enlarging human capital and raising its quality. This has been appeared by Namibia as it was positioned the second and fifth individually as far as mechanical advancement and commonness of outside innovation permitting in the seriousness report. Be that as it may, firm level retention of this innovation stays low as the nation was positioned fif teenth. From this case we can discover that the utilization of innovation requires gifted work power. As prior called attention to, interest in human capital stays a basic issue for Namibia and other creating nations. The utilization of innovation requires supporting framework, for example, great media transmission and vitality specifically. (?) Countries, for example, Australia, Chile, Malaysia, and Spain have reacted by creating cross-sectoral strategy structures to advance science, innovation, and development. Inside Sub-Saharan Africa, Mozambique, Rwanda, and South Africa have driven the route with comparative cross-cutting systems. Other SSA nations that have created national science and innovation arrangements since 2000 incorporate Ethiopia, Ghana, Lesotho, Malawi, Senegal, Tanzania, Uganda, Zambia, and Zimbabwe (Mouton 2008). Better instruction framework can help the creating nations in †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. Pre Requisites for innovation make up for lost time Innovation ingestion is regularly viewed as a pre essential for separating a significant expense economy and making a monetary serious market globally. The underlying hole for nations which are attempting to find innovation ought not be unreasonably wide for them to have the option to ingest information from mechanical pioneers. In addition, newbies must have, or make, adequate retention abilities. In this specific circumstance, adequate ingestion capacities are portrayed as having qualified specialists who can comprehend outside information overflows and perceive their incentive in activity. Creating nations need a solid human capital base that will have the option to comprehend the new inventive frameworks that have been set up by the propelled nations, subsequently they need very much created logical, building and specialized abilities. Cohen and Levinthal (1990 pg .129) propose that collected information increments both the capacity to try new thoughts. On the off chance that the supply of information is expanded, all in all, extra learning will be encouraged. The development of information increases the value of the countrys capacity to adjust to new thoughts subsequently beco

Saturday, August 22, 2020

Character analysis of Christian Darling in The Eighty-Yard Run short Essay

Character examination of Christian Darling in The Eighty-Yard Run short story - Essay Example Sweetheart weds Louise Tucker, his wonderful school sweetheart, and moves to New York. He works for his well off dad in-law, an ink maker, who ends it all after the Crash of 1929. Louise proceeds to turn into a fruitful magazine editorial manager. Then again, Darling can't discover out of the changed conditions of his life. He concedes that he is a disappointment. The story is worked round Darling’s and Louise’s differentiating perspectives towards life. Darling’s portrayal is the principle string of the account and the activity of the story spins round it. â€Å"The Eighty-Yard Run† subtleties how Darling’s character ruins his conjugal relationship and prompts his acknowledgment of disappointment at the age of thirty-five. The trademark attribute of Darling’s character is his adolescence and his refusal to adjust to new conditions. Darling’s disappointment in life is because of his adolescence and protection from change. Dear exhibits a juvenile disposition towards life. He is whimsically satisfied with his ‘eighty-yard run’ and saturates it with undue significance. He recalls â€Å"feeling wonderful,† - â€Å"listening to the acclaim and yells of the understudies along the sidelines† (Shaw, Year, 1-4). He relaxes in the congrats, the whining of the chiefs and the captain’s endorsing conjecture: â€Å"Darling, youre going to go puts in the following two years† (Shaw, Year, 2-1). He envisions his entrance onto the field in the coming game against Illinois, certain that, when the observers cheered, â€Å"part of that gigantic salute would be for him† (Shaw, Year, 2-5). He is extremely conceited about his run and gloats to Louise, â€Å"I got the mentor in the palm of my hand† (Shaw, 3-2). His ‘eighty-yard run’ gives him a passing acclaim with the school group, and he is smugly mindful of being â€Å"an significant figure† nearby (Shaw, 3-9). In actuality, Darling’s splendid run happens just at a training meeting. It moves him from being a second

Wednesday, July 29, 2020

Symptoms of Acute Alcohol Poisoning

Symptoms of Acute Alcohol Poisoning Addiction Alcohol Use Binge Drinking Print Symptoms of Acute Alcohol Poisoning Passing Out From Drinking Could Indicate Danger By Buddy T facebook twitter Buddy T is an anonymous writer and founding member of the Online Al-Anon Outreach Committee with decades of experience writing about alcoholism. Learn about our editorial policy Buddy T Medically reviewed by Medically reviewed by Daniel B. Block, MD on November 21, 2019 twitter linkedin Daniel B. Block, MD, is an award-winning, board-certified psychiatrist who operates a private practice in Pennsylvania. Learn about our Medical Review Board Daniel B. Block, MD Updated on February 23, 2020 PeopleImages/Getty Images   More in Addiction Alcohol Use Binge Drinking Withdrawal and Relapse Children of Alcoholics Drunk Driving Addictive Behaviors Drug Use Nicotine Use Coping and Recovery More than 2,200 people die from alcohol poisoning each year, which is an average of six people per day, according to the Centers for Disease Control and Prevention.?? Most fatalities are men and three in four people are between the ages of 35 and 65. The number of deaths varies widely from state to state. For example, there are 5.3 deaths per million residents in Alabama, but 46.5 deaths per million in Alaska. Causes of Alcohol Poisoning Too much alcohol in your bloodstream causes the areas of your brain that support breathing, your heart rate, and other basic life-supporting functions to start to shut down. In other words, your friend who drank way too much, may not just be sleeping it off. If he is experiencing an episode of acute alcohol poisoning, drinking too much too quickly, his condition could lead to coma and even death if you do not intervene.?? Alcohol poisoning affects the brain, blood vessels, and liver.  Rapid fluid ingestion  alters the fluid concentration in your body, potentially disrupting your fluid and electrolyte balance. Children or adults can get alcohol poisoning. When it comes to kids, and maybe adults too, your thoughts might immediately jump to the liquor cabinet, but remember that another household product that contains alcohol, such as a cooking extract, or medicinal tincture, could be the culprit. Symptoms Learning the symptoms of acute alcohol poisoning can help you tell the difference between a friend who is drunk and passed out and a person who is unconscious due to acute alcohol poisoning. ConfusionPassing outSeizuresSlow heart rateNo gag reflex, which prevents choking when vomitingClammy or blue-tinged skin and extremely low body temperature (hypothermia)Breathing slowly or irregularly (less than eight times a minute or ten seconds or more between any two breaths)Vomiting while passed out and doesnt wake up during or after vomiting Remember, your friend does not have to have all the symptoms to be at risk. And anyone who cannot be awakened or is unconscious is at risk of dying.?? What to Do If You Think Someone Has Alcohol Poisoning Here are the steps to take if you think someone has alcohol poisoning:Call 9-1-1 immediately, even if you dont see the classic signs or symptoms. Do not hesitate and dont think about any legal ramifications. Your friends life could depend on your quick response.Prepare yourself to provide information to the emergency personnel or the hospital, including the type and amount of alcohol and when your friend drank it.Do not leave your friend alone and continue to try to revive them. Turn him on his side, so he will be less likely to choke if he vomits.If your friend is vomiting, try to keep him sitting up and awake.Watch his breathing closely. If he stops breathing be prepared to perform  CPR. If you dont know how to perform CPR, try to find someone who does.Do not give your friend or coffee or put him or her into a cold shower. Despite common myths, these methods do not reduce the effects of alcohol poisoning. Treatment Calling 911 and keeping your friend safe until help arrives is the first step to safely treating someone with alcohol poisoning. Once at the hospital (or even en route) a medical professional may give a person with alcohol poisoning intravenous (IV) fluids to replace the fluid loss from vomiting and to balance any fluid and electrolyte disruption in the body caused by the excessive amounts of alcohol.?? Oxygen may also be administered for respiratory support, especially if the person is experiencing irregular or slowed breathing, in addition to medication to regulate any dips in blood pressure. If the person is experiencing seizures, a short term anticonvulsant medication will be given to stop the seizures.

Friday, May 22, 2020

Analysis Of Rene Descartes s Meditations On First...

Philosophy Essay 1 Rene Descartes was born in in La Haye, France, in 1596 and he studied at La Fleche Jesuit College and University of Poitiers. Descartes also lived in Germany, Holland and Sweden. He then worked in the army as a private councillor and then as a court philosopher. Descartes book ‘Meditations on First Philosophy’ was first published in 1641. The edition used to write this essay was edited by John Cottingham and was published by the Cambridge University Press in 1996. Descartes was the first philosophy to be influenced by autonomy and physics and he also worked it all out for himself by not accepting the views of previous philosophers. Through the meditations, the meditator explores the ontological questions about being,†¦show more content†¦The argument in Descartes second meditation is that he wants to prove to the reader that the human mind is better known than the human body. In this meditation Descartes is looking for basic belief which has to provide some foundation for knowledge. The meditator is going to do this through a series of Sceptical doubts. First he will doubt his sense-perception because the evidence received from the outer-senses can be contradictory. This means that he will call all his sense into doubt as if he had no senses at all. Descartes will also doubt the physical world by believing that we might be dreaming. Descartes finally begins to doubt reality and the existence of God. However, he also believes that there is a presence of a type of God or evil deceiver. Descartes then begins to start his first statement with ‘I think’. He believes that if he is having these doubts and that a god or evil deceiver is also sending him doubts that he must exist. In the First Meditation, Descartes introduced the method of doubt to the reader. He then starts to use this method, he then begins to put all his thoughts into doubt and he begins to wonder where his thoughts have come from; if they have been implanted him in by a god or an evil deceiver. By this point Descartes has convinced himself that nothing is certain or that a god or evil deceiver has implanted these doubts into his mind. This means that if either of these points is trueShow MoreRelatedAnalysis Of Rene Descartes s Meditations On First Philosophy1066 Words   |  5 Pageswhat is reality? Among these writers were Renà ¨ Descartes and George Berkeley, who respectively argued that everything perceived must be real due to God being unable to deceive, and that the physical world only exists in one’s mind. In my view, it is not certain that the physical world is real, but one should act as if it is. Renà ¨ Descartes, in Meditations on First Philosophy, wrote each section after successive â€Å"meditations.† In Descartes’s first meditation, he claims it is unable to be proven whetherRead MoreDescartes’ Cogito Argument Successfully Shows the Evil Demon Argument is Unsound888 Words   |  4 PagesDoes Descartes’ Cogito argument successfully show that the Evil Demon Argument is unsound? In this essay I will attempt to show that the philosopher, Renà ¨ Descartes’ Cogito Argument successfully proves the Evil Demon Argument to be unsound. By an analysis of the structure of the arguments and what they prove, I will show the evil demon argument to be unsound. An argument is unsound when the premises as false and the argument is invalid. This analysis of both structure and content will eventuateRead MoreThe Dream Inside Of A Dream By Christopher Nolan1683 Words   |  7 PagesFinal Paper: Descartes The possibility of having a dream inside of a dream is an idea that has been discussed far and wide. However, before Inception came out in 2010 by director Christopher Nolan, many people in the modern world may not have ever considered this idea. Nonetheless, this idea of â€Å"a dream inside a dream† has been around since 1640, when Rene Descartes published Meditations. In Inception, Christopher Nolan uses Descartes ideas to enhance the storyline of his film. In this paperRead More Rene Descartes Essay1094 Words   |  5 PagesRene Descartes was a famous French mathematician, scientist and philosopher. He was arguably the first major philosopher in the modern era to make a serious effort to defeat skepticism. His views about knowledge and certainty, as well as his views about the relationship between mind and body have been very influential over the last three centuries. Descartes was born at La Haye (now called Descartes), and educated at the Jesuit College of La Flà ¨che between 1606 and 1614. Descartes later claimedRead MoreThe On First Philosophy By Rene Descartes1699 Words   |  7 PagesIn his work Meditations on First Philosophy, published in 1641, Renà © Descartes sets out to establish a set of indubitable truths for the sciences. He begins by discarding all of his beliefs, then works to rebuild his beliefs based on careful thought. Descartes clearly states this goal, saying in the First Meditation, â€Å"I will work my way up†¦ I will accomplish this by putting aside everything that admits of the least doubt† (I, 17). He is able to establish his own existence, but struggles to move beyondRead MoreProposed Seven Philosophers On The Existence Of God And Their Development Of These Ideas1413 Words   |  6 Pagesphilosophers are as follows: (1) Socrates, (2) Plato, (3) Aristotle, (4) Francis Bacon, (5) St. Augustine, (6) Thomas A quinas, and (7) Rene DesCartes. The specific three I want to focus on being; St. Augustine, Thomas Aquinas and Rene Descartes. Lastly, I will proceed to relate their ideas on the existence of God and their development of these ideas. St. Augustine s epistemology is rationalization. In his argument for the existence of God, he is referring to varying degrees of perfection otherwiseRead MoreA Brief Biography of Rene Descartes1580 Words   |  6 Pagesworks of philosopher Rene Descartes, who had endorsed the mechanistic conception of the world and the human body by coining notions such as mind, substance, and the knowledge argument; although his notions were not always accepted, he managed to provide valid support. Born in France, Rene Descartes, dubbed The Father of Modern Philosophy was, in a way, a Renaissance man having contributed influence amongst subjects such science, mathematics, psychology, and philosophy. Descartes was the medium ofRead MoreAnalysis Of Descartes Meditations On First Philosophy Essay1758 Words   |  8 Pages The Role of God in Descartes’ Meditations on First Philosophy In his work Meditations on First Philosophy, published in 1641, Renà © Descartes sets out to establish a set of indubitable truths for the sciences. He begins by discarding all of his beliefs, then works to rebuild his beliefs based on careful thought. Descartes clearly states this goal, saying in the First Meditation, â€Å"I will work my way up†¦ I will accomplish this by putting aside everything that admits of the least doubt† (I, 17). HeRead MoreEssay on Descartes Failure4852 Words   |  20 PagesDescartes Failure In his Meditations on First Philosophy, Descartes strives first and foremost to provide an infallibly justified foundation for the empirical sciences, and second to prove the existence of God. I will focus on the first and second meditations in my attempt to show that, in his skepticism of the sources of knowledge, he fails to follow the rules he has set out in the Discourse on Method. First I claim that Descartes fails to draw the distinction between pure sensation andRead MoreLanguage and the Destiny of Man12402 Words   |  50 PagesÅžtefan Afloroaei / Descartes and the â€Å"metaphysical dualism† Descartes and the â€Å"metaphysical dualism†: Excesses in interpreting a classic* Al.I. Cuza University of Iasi Abstract The article focuses on one of the most serious accusations brought against Descartes and modern philosophy, namely â€Å"the dualism of substance†. The accusers claim that the human body and soul were viewed as completely separate; consequently, their relationship as such and the united being of man become incomprehensible. As Analysis Of Rene Descartes s Meditations On First... Since seemingly the dawn of humankind, there has been a question that has prompted many different answers: what is reality? Among these writers were Renà ¨ Descartes and George Berkeley, who respectively argued that everything perceived must be real due to God being unable to deceive, and that the physical world only exists in one’s mind. In my view, it is not certain that the physical world is real, but one should act as if it is. Renà ¨ Descartes, in Meditations on First Philosophy, wrote each section after successive â€Å"meditations.† In Descartes’s first meditation, he claims it is unable to be proven whether anything besides one’s mind actually exists, using dreams as an example. He mentions how dreams deceive him into believing things†¦show more content†¦As an example of how things may not be as they seem, he takes a â€Å"piece of wax [that was] taken...from [a] honeycomb† (464). He notes that â€Å"it has not yet lost all the honey flavor,† â€Å"retains some of the the scent of the flowers from which it was collected,† and that â€Å"its color, shape, and size are manifest† (464). Then, however, as he brings it close to a fire, â€Å"the remaining traces of the honey flavor [disappear],† â€Å"the scent [vanishes],† â€Å"the color [changes],† the original shape [disappears],† â€Å"its size [increases],† and it becomes â€Å"liquid and hot† (464). Then he asks: â€Å"what was there in the wax that was so distinctly grasped† (465)? He theorizes that the wax was never what it originally seemed, but merely dressed up in other things that gave it its appearance. Going off of this, he asks if this is an isolated incident—implying it is not. In his third meditation, Descartes’s view changes drastically. He says, considering that it is self-evident that â€Å"something cannot come into being out of nothing, and also that what is more perfect (that is, what contains in itself more reality) cannot come into being from what is less perfect† (468), God not only has to exist as the source of everything, but he must be perfect. Going off of this, he puts forward that God â€Å"cannot be a deceiver, for it isShow MoreRelatedAnalysis Of Rene Descartes s Meditations On First Philosophy 1399 Words   |  6 PagesPhilosophy Essay 1 Rene Descartes was born in in La Haye, France, in 1596 and he studied at La Fleche Jesuit College and University of Poitiers. Descartes also lived in Germany, Holland and Sweden. He then worked in the army as a private councillor and then as a court philosopher. Descartes book ‘Meditations on First Philosophy’ was first published in 1641. The edition used to write this essay was edited by John Cottingham and was published by the Cambridge University Press in 1996. Descartes wasRead MoreDescartes’ Cogito Argument Successfully Shows the Evil Demon Argument is Unsound888 Words   |  4 PagesDoes Descartes’ Cogito argument successfully show that the Evil Demon Argument is unsound? In this essay I will attempt to show that the philosopher, Renà ¨ Descartes’ Cogito Argument successfully proves the Evil Demon Argument to be unsound. By an analysis of the structure of the arguments and what they prove, I will show the evil demon argument to be unsound. An argument is unsound when the premises as false and the argument is invalid. This analysis of both structure and content will eventuateRead MoreThe Dream Inside Of A Dream By Christopher Nolan1683 Words   |  7 PagesFinal Paper: Descartes The possibility of having a dream inside of a dream is an idea that has been discussed far and wide. However, before Inception came out in 2010 by director Christopher Nolan, many people in the modern world may not have ever considered this idea. Nonetheless, this idea of â€Å"a dream inside a dream† has been around since 1640, when Rene Descartes published Meditations. In Inception, Christopher Nolan uses Descartes ideas to enhance the storyline of his film. In this paperRead More Rene Descartes Essay1094 Words   |  5 PagesRene Descartes was a famous French mathematician, scientist and philosopher. He was arguably the first major philosopher in the modern era to make a serious effort to defeat skepticism. His views about knowledge and certainty, as well as his views about the relationship between mind and body have been very influential over the last three centuries. Descartes was born at La Haye (now called Descartes), and educated at the Jesuit College of La Flà ¨che between 1606 and 1614. Descartes later claimedRead MoreThe On First Philosophy By Rene Descartes1699 Words   |  7 PagesIn his work Meditations on First Philosophy, published in 1641, Renà © Descartes sets out to establish a set of indubitable truths for the sciences. He begins by discarding all of his beliefs, then works to rebuild his beliefs based on careful thought. Descartes clearly states this goal, saying in the First Meditation, â€Å"I will work my way up†¦ I will accomplish this by putting aside everything that admits of the least doubt† (I, 17). He is able to establish his own existence, but struggles to move beyondRead MoreProposed Seven Philosophers On The Existence Of God And Their Development Of These Ideas1413 Words   |  6 Pagesphilosophers are as follows: (1) Socrates, (2) Plato, (3) Aristotle, (4) Francis Bacon, (5) St. Augustine, (6) Thomas A quinas, and (7) Rene DesCartes. The specific three I want to focus on being; St. Augustine, Thomas Aquinas and Rene Descartes. Lastly, I will proceed to relate their ideas on the existence of God and their development of these ideas. St. Augustine s epistemology is rationalization. In his argument for the existence of God, he is referring to varying degrees of perfection otherwiseRead MoreA Brief Biography of Rene Descartes1580 Words   |  6 Pagesworks of philosopher Rene Descartes, who had endorsed the mechanistic conception of the world and the human body by coining notions such as mind, substance, and the knowledge argument; although his notions were not always accepted, he managed to provide valid support. Born in France, Rene Descartes, dubbed The Father of Modern Philosophy was, in a way, a Renaissance man having contributed influence amongst subjects such science, mathematics, psychology, and philosophy. Descartes was the medium ofRead MoreAnalysis Of Descartes Meditations On First Philosophy Essay1758 Words   |  8 Pages The Role of God in Descartes’ Meditations on First Philosophy In his work Meditations on First Philosophy, published in 1641, Renà © Descartes sets out to establish a set of indubitable truths for the sciences. He begins by discarding all of his beliefs, then works to rebuild his beliefs based on careful thought. Descartes clearly states this goal, saying in the First Meditation, â€Å"I will work my way up†¦ I will accomplish this by putting aside everything that admits of the least doubt† (I, 17). HeRead MoreEssay on Descartes Failure4852 Words   |  20 PagesDescartes Failure In his Meditations on First Philosophy, Descartes strives first and foremost to provide an infallibly justified foundation for the empirical sciences, and second to prove the existence of God. I will focus on the first and second meditations in my attempt to show that, in his skepticism of the sources of knowledge, he fails to follow the rules he has set out in the Discourse on Method. First I claim that Descartes fails to draw the distinction between pure sensation andRead MoreLanguage and the Destiny of Man12402 Words   |  50 PagesÅžtefan Afloroaei / Descartes and the â€Å"metaphysical dualism† Descartes and the â€Å"metaphysical dualism†: Excesses in interpreting a classic* Al.I. Cuza University of Iasi Abstract The article focuses on one of the most serious accusations brought against Descartes and modern philosophy, namely â€Å"the dualism of substance†. The accusers claim that the human body and soul were viewed as completely separate; consequently, their relationship as such and the united being of man become incomprehensible. As

Saturday, May 9, 2020

A Startling Fact about Scholarship Essays Examples about Yourself Uncovered

A Startling Fact about Scholarship Essays Examples about Yourself Uncovered Here's What I Know About Scholarship Essays Examples about Yourself Every student demands help with homework from time to time. This scholarship could offset a few of the costs and decrease my workload for a whole. The scholarships you find are likely to fit into specific themes that you must have the ability to identify as a way to save your family time, frustration, stress, and above all money. That means you can be ensured of great scholarship essay examples. Scholarship essay prompts are extremely tricky, so you ought to read and re-read it multiple times to spot key themes. It is not a paper where you can forgive yourself misspellings or formatting inaccuracy. What's a scholarship essay. Keep in mind your introduction, the very first paragraph of an essay, needs to be short and catchy. For me, writing essays isn't an easy job. The way the essay is written will predict the writers knowledge on a particular topic. It's a fact that the length of an essay is dependent on the subject. Write an outline, creating a list of the crucial features you are ready to include to the text. Essay writing should involve a crystal clear grasp of the concerned undertaking. When these essays may appear to be a little step toward your future, they're a step nonetheless. Both examples handle the exact theme (sick parent) but utilize various approaches. The Honest to Goodness Truth on Scholarship Essays Examples about Yourself Even though this kind of essay should only be 250 words long, you should organize your ideas ahead of time. By the close of the essay, the reader needs to have a complete comprehension of who you are and what you would like to accomplish. When you inform u s about all of the paper information, we'll begin trying to find an appropriate writer for your paper. You have to know the objective of your scholarship before writing the piece. Also, you're ready to purchase essay online cheap in the event of time lack. Having us to fix any of the issues that you may face when coming up with scholarship essay topics will be advisable for you. Unfortunately, my story isn't one of a sort. Write an anecdote, a quote, an intriguing fact or a story from your private life to illustrate what you are likely to write about later on. Students lead busy lives and frequently forget about an approaching deadline. Essays are often necessary for scholarship applications. Scholarship essays shouldn't be considered a burden since they are your gateway to land entrance into a prestigious university with a great deal of benefits and perks that have the scholarship. For your college scholarship essay, you might be asked about your career objectives. Finding out how to compose an ideal scholarship essay is the trick to winning handsome scholarships. Instead, mention the way your education can assist your career. If you've already graduated from college or university and are looking for a very good job, you will need to get a persuasive resume to impress your future employer. The Demise of Scholarship Essays Examples about Yourself Your CV is the initial step for your fantasy job as it's the first issue to be noticed by the recruiters and by thinking about the different CVs they shortlist the candidates from a range of applications they've attained. Hands-on experience is the best teaching mechanism an individual can employ through life. There's nobody approach to compose a winning scholarship application. Essay writing is believed to be an extremely significant part academic life that a student can't overlook. Such essays are from time to time written in a series so they cover the whole scope of the theme. In some instances, you might find it challenging to compose as a result of inadequate abilities, and thus a sample winning scholarship essays would provide the guidance you demand. That means you can order for our high school scholarship essay examples without needing to be concerned about your private details. A scholarship essay is a significant document which is used in the processes of scholarship application. It is a good idea to look for the one which has a superior reputation and offers high-quality papers at inexpensive prices. Bear in mind, on the exterior of the envelope, list the name of the particular scholarship you're inquiring about.

Wednesday, May 6, 2020

The Industry Structure The Behavior of Firms in the PC Industry Free Essays

In this paper I will discuss the industry structure and the behavior of firms in the Personal Computer Industry. The personal computer industry has five leaders: Compaq Computer Corporation (CCC), Dell Computer Corporation, International Business Machines (IBM), Hewlett-Packard, and Gateway, (Industry Survey, Apr. 2000). We will write a custom essay sample on The Industry Structure The Behavior of Firms in the PC Industry or any similar topic only for you Order Now The PC industry, as discussed in the paper, is comprised only of home/business use machines, not mainframes, databases, or any kind of servers or super-computers. The PC industry is a fast-growing, consumer-based oligopoly. I will prove the latter through the use of industry characteristics and firm behaviors by giving an overview of each leading firm and their behaviors†, then by combining them into an industry analysis. The companies will be addressed from top leader to bottom. Compaq Computer Corporation,(CCC) is the current industry leader. CCC boasts a 1999 market share of 12. 8%. However, this figure has declined slightly from its 1998 share of 13. 4%. The dip is due to Dell Computer Corp. â€Å"s heavy presence in the small PC market, (Industry Survey, Apr. 2000). Compaq has a wide range of PC products from smaller, less expensive machines to more costly, high-tech systems. CCC has been most successful with their smaller machines, targeted to the home/family segment, because they are able to sell large quantities. However, Compaq has been unsuccessful in retaining customers because most of them were pleased with their smaller machines and did not upgrade to CCC†s more expensive, high-tech systems,(Hamblen 1-2). Customer retention has been a problem for the forty billion-dollar company, (Hamblen 1-2). It is my assessment that Compaq does still remain the leader because their products are very easy to buy for the uneducated consumer. You may simply walk into the WIZ or BEST BUY and there are five or so Compaq machines all competitively priced with a good range of attributes, usually not the best that a veteran user would require. For instance CCC†s newest product, the iPac, is a very simple-to-use, inexpensive machine. It is supposed to satisfy business workers† needs for a useful computer at low cost,(Wildstrom 1-2). Another problem in CCC†s not-to-distant future is their distribution costs. With the use of the Internet, competitors have been able to reduce and even eliminate distribution costs. To follow suit Compaq plans to increase direct sales in the future, according to Micheal Capellas, CEO (Hamblen 4). The future for CCC is quite hazy. Despite the sales numbers and the heavy bottom line, CCC†s stock price has sat down in the low $30†³s,(Hamblen 1). Competition is increasing daily and Compaq needs to distinguish itself in the marketplace. They†ve already experienced a decline in markets share, only they can change their fate. Dell Computer Corporation, the second leading computer manufacturer, began by selling PC†s directly to consumers. Their first customers ordered over the phone and Wold Wide Web. To this day Dell still has no brick and mortar retailers and does not distribute its product to resellers. In the business to business market Dell has excelled, but until recently, the profitable company was not so profitable in the home-user segment,(Industry Survey, Apr. 2000). The company†s new strategy, to gain market share, has proven very effective. Dell now posts a 62% gain in world wide PC shipments and a 2. 6 share-point gain from 8. 2% in `98 to 10. 8% in `99,(Industry Survey, Apr. 2000). Recently Dell†s presence has been felt in the growing PC market. This has forced competitors to be very careful about pricing in this highly elastic industry. Dell†s profitability is also notable, since it has minimal distribution costs and does very little advertising Dell is extremely profitable. However, rough times may be on the horizon for Dell. Analysts are worried because profit growth projections were cut at least 10% by CFO Thomas Meredith, who declared he is only trying to set more realistic goals and that the company will still post growth, (Burrows 1-2). Recently Dell has made some key moves that should boost revenues including beefing-up its web site and a joint venture with Internet giant AOL, (Money 1-2). Dell Computer Corporation is still a major player in the PC industry and will continue to be in the future. Unlike Dell and Compaq, IBM has not had extreme success in the PC market. It is known that leaders at IBM never believed that the PC would be an important device and that only a small portion of the population would ever own a PC. Obviously, they were very wrong. IBM has not done a bad job catching up to the pack, though; it now has the number-three market share of 7. 6%, (Industry Survey, Apr. 2000). IBM plans some new strategies after its low ranking in the PC market. This new strategy is to end all retail selling and go completely direct, IBM plans to sell its Aptiva system exclusively over the Internet in the near future, (Industry Survey, Apr. 000). This will lower costs and possibly increase the bottom line for the computer giant. Like IBM, Hewlett-Packard made one mistake and cost itself billions of dollars in revenues. HP is a large electronics conglomerate. HP manufactures everything from calculators to top-secret government appliances. For HP the PC market is one of many. Originally Hewlett-Packard was the standard in computer electronics; however, this is not reality today. HP†s reputation declined through the `80s and early `90s because of poor quality management. To regain the respect they had lost the marketing and engineering departments at HP worked their fingers to the bone to create a new image for the company. This was very effective; today HP owns a modest 6. 2% of the PC market and a very healthy reputation for quality PC†s and peripherals, (Industry Survey, Apr. 2000). HP has had some growth in the past few years but has failed to match the industry growth rates. The company†s years of poor quality put a considerable hurt on their future growth; while HP was busy filling in the hole it dug for itself, industry leaders like Compaq and Dell were basking in their success. How to cite The Industry Structure The Behavior of Firms in the PC Industry, Essay examples

Wednesday, April 29, 2020

Verbal Communication Essay Research Paper Child AbuseWhat free essay sample

Verbal Communication Essay, Research Paper Child Abuse What is child abuse? It is the physical or emotional maltreatment of a kid by a parent, guardian, or other individual. Reports of kid maltreatment, including sexual maltreatment, whipping, and slaying, have climbed in the United States and some governments believe that the figure of instances is mostly under reported. Child disregard is sometimes included in legal definitions of kid maltreatment to cover cases of malnutrition, abandonment, and unequal attention of a kid # 8217 ; s safety. When reported, kid maltreatment instances are complicated by unequal Foster attention services and a legal system that has problem suiting the suggestible nature of kids, who are frequently developmentally unable to separate fact from pretend ( Hay, 1996 ) . Many kids suffer at the custodies of grownups # 8211 ; frequently their ain parents. They are beaten, kicked, thrown into walls, and/or burned with coffin nails. They have their caputs held under the H2O of lavatory bowls, are scalded by hot H2O or they are forced to stand in stop deading showers until they pass out. We will write a custom essay sample on Verbal Communication Essay Research Paper Child AbuseWhat or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page A kid could be stuffed into running rinsing machines or sexually molested, suffer from disregard in the signifiers of famishment and deficiency of medical attending, and still travel unnoticed by foreigners. In fact, it is estimated that three kids die every twenty-four hours in the U.S. entirely from one signifier of kid maltreatment or another. It is a nauseating pattern that has no set criterion of regulations to complete off the persisting job. Different provinces have different methods and bureaus to assist forestall maltreatment in the place, some work rather good while others bomb # 8211 ; a unsafe gamble when it comes to the life or mental province of a kid. I have seen kid abuse first manus and up near. I serve on the Advisory Board and Board of Directors for Lutheran Social Services, Foster Care Division of Michigan. It is shocking, immoral and bosom wrenching to see how grownups can handle kids. The married woman and myself have fostered many kids. They have come out of some really dysfunctional places. Some of the kids we fostered have been sexually molested and severely abuse by their ain parents. What makes it so bad is that most of the kids think that this is acceptable behaviour and would travel back to their places if they could. We had one small male child who would instead eat out of the refuse than sit at the tabular array to eat. We fostered another household of two male childs and two misss. Their male parent and uncle had sexually abused them all. These kids ranged from 7 to 12 old ages of age. While these kids were populating with us, we had caught them several times commiting each other in a sexual mode. They thought thi s was normal and acceptable behaviour. I besides know of a batch of instances where kids even die at the custodies of their on parents. What has our society go? You find in a batch of instance where the culprit has been perpetrated. Approximately 1 in 6 male childs is sexually abused before the age of 16. Dr. William C. Holmes of the University of Pennsylvania School of Medicine said that when sexually abused male childs are non treated, society must subsequently cover with the ensuing jobs, including offenses, self-destruction, drug usage, and more sexual maltreatment. This rhythm must be broken. This job affects everyone. Most child maltreatment takes topographic point in the place and is started by individuals are know to and trusted by the kid. Even though it h as been widely publicized, maltreatment in day-care and foster-care scenes histories for merely a little figure of confirmed instances of kid maltreatment. In 1996, merely two per centum of all confirmed instances of kid maltreatment occurred in these scenes. Child abuse if 15 times more likely to happen in households where spousal maltreatment occurs. Children are three times more likely to be abused by their male parents than by their female parents. No differences have been found in the incidence of kid maltreatment in rural versus urban countries. Following are the types of maltreatment and the per centums of the different types. Neglect # 8211 ; 54 % Physical maltreatment # 8211 ; 25 % Sexual maltreatment # 8211 ; 11 % Emotional maltreatment # 8211 ; 3 % Other # 8211 ; 7 % ( Davis, 1998 ) . There are many parents that need aid in rearing. One of the ways to assist parents is to do certain their basic demands are met. Until parents # 8217 ; basic demands are met, they may happen it hard to run into the demands of their kids. The first thing parents need is aid in run intoing their basic demands for nutrient, shelter, vesture, safety and medical attention, reding and ECT. Merely when these demands are met can higher demands be addressed ( Rushton, 1997 ) . Another way8 to assist should be to place and handle parents who abuse intoxicant or drugs, and place and advocate parents who suffer from spousal maltreatment. Identifying and handling parents with psychologic jobs is besides of import. Other issues that need attending include fiscal concerns, and employment and legal jobs. Supplying an empathic ear and being a beginning of referral for aid with these issues may take doctors a long manner toward fostering destitute parents. The following higher degree of demand includ es instruction about clip direction and budgeting accomplishments, emphasis direction, get bying and rearing accomplishments such as appropriate subject, cognition of kid development, nutrition and eating jobs, and safety issues ( Rushton, 1997 ) . In my decision, many things need to go on at international, national, province and community degrees to forestall kid maltreatment. Surveies have shown that states with the most generous societal services have the lowest rate of kid homicide. Peoples should buttonhole for greater handiness of drug and intoxicant intervention plans, more shelters for the homeless, more accessible mental wellness attention and more shelters for abused adult females and kids. These plans and those that provide rearing accomplishments, support groups and reprieve attention for parents and attention givers should be available in every community. Child maltreatment is a complex job with many causes, it is of import that people non take a defeatist attitude toward its bar. Despite the absence of strong grounds to steer preventative attempts, society can make things to seek to forestall maltreatment. Showing increased concern for the parents or health professionals and increasing efforts to heighten their accomplishments as parents or attention givers may assist salvage the most vulnerable people, our kids, from the incubus of maltreatment and disregard. Plants Cited Hay, T. # 8220 ; Social Interventions to Prevent Child Abuse and Neglect. # 8221 ; Child Welfare 5 February 1996: 379-403. Rushton, Frank. # 8220 ; The Role of Health Care in Child Abuse and Neglect Prevention. # 8221 ; Pediatricss March 1997: 133-136. Davis, Laura. Stop Domestic Violence. New York: Macmillan, 1998.

Friday, March 20, 2020

t-box case study

t-box case study Faika Seda MORALIMBA- 2013310101641. Briefly explain how T-box revolutionizes the traditional product approach in the apparel industry. Do you think that this is a reasonable risk to take? Why? Why not?T-box was created by the top management team of Boyner Group in 2003. Boyner Group is the largest non-food retailer in Turkey since 1981. The group sells famous local and international brands of apparel, accessories, cosmetics and home appliances. Boyner Group targets middle-upper and upper income levels with a classic taste of fashion with high-class brands such as Network, Alt„Â ±ny„Â ±ld„Â ±z and Fabrika. In contrast with Boyner, T-box targets a younger market with a hip taste and a morbid sense of humor. T-box transforms textile products into fast moving consumer goods (FMCG), moving beyond the traditional understanding that clothes and accessories are rather in the shopping goods category. It became convenience good. Its target market volume is large, distribution i s very extensive.English: Logo of the clothing brand Cure ApparelPrices are not expensive.They wanted to create a new market and decided to treat the products under the clothing brand T-box as if they were Fast Moving Consumer Goods. Small packages which are fit in a hand, easy to carry especially for travel purposes, low priced products such as headbands, wallets, lighters and condoms at the cash desk has also allowed the brand to be perceived as "last minute, immediate purchase" brand and most importantly to support the FMCG image of the so-called fashion products, making them similar to the packaged fruit juices, toilet papers or house cleaning supplies lined up on a supermarket shelf.The approach to the design of packaging and the presentation of the packs at the point of purchase had a great effect on sales.The other step of revolution is that 1 euro/cent exists in the package of the...

Wednesday, March 4, 2020

Washington Irvings Famous Story of a Sleeping Man

Washington Irving's Famous Story of a Sleeping Man Rip van Winkle  is an 1819 story by Washington Irving, American short-story writer. The story was published as part of The Sketch Book of Geoffrey Crayon, and was based on a German fairy tale. It chronicles the story of a man who falls asleep in the Catskills just before the American Revolution, and wakes up 20 years later to a completely different society.   Rip ends up in the mountains in the first place while trying to escape his nagging wife, and meets a man struggling with a heavy keg of moonshine. He helps the man carry it to a hollow where they encounter strange men playing a game of ninepins. Rip drinks some of their moonshine, and falls asleep 20 years later with a rusted musket and a long beard. He later learns that the man with the keg was the ghost of Henry Hudson.   Here are some questions for study and discussion about Rip van Winkle: Who are the strange men that Rip encounters in the hollow? Is it helpful to know that the story is based on a German fairy tale? Why or why not? Is Rips long sleep a reward (perhaps for helping the men playing ninepins) or a punishment (for being a generally lazy guy)? What is the portrayal of women in the story, including that of Rips wife Dame van Winkle? Can you think of a more contemporary story where a nagging wife is so central to a storys plot? How does Irving reveal character in Rip van Winkle? Compare/Contrast Rip van Winkle with Gulliver of Gullivers Travels by Jonathan Swift. Are there other characters in literature that compare to Rip van Winkle? Is Rip van Winkle consistent in his actions? Is he a fully-developed character? Discuss some of the symbols in Rip Van Winkle. Compare Rip van Winkle  with The Legend of Sleepy Hollow. How are they similar? How are they different? How essential is the setting to the story? Could the story have taken place anywhere else? What if the story had been set before and after the Civil War, or the War of 1812? How realistic is Irvings depiction of the Catskills? Why did he choose to set the story there? How does time figure into the story? Why was Rips slumber 20 years long, and not 10 years or 30 years? What would a sequel to Rip van Winkle have looked like? What would you expect Rip would be doing in another 20 years time? Is Rip van Winkle a tragedy or a comedy? Is there a central moral or lesson to be learned? Is this a childrens story? Why or why not?

Sunday, February 16, 2020

Individual Personal Reflection Paper Assignment Example | Topics and Well Written Essays - 500 words

Individual Personal Reflection Paper - Assignment Example ve learnt that Critical thinking, among other things, makes one think rationally and with more clarity irrespective of the field one is in; education, law, medicine, finance, or management. Critical thinking is a vital component as it enhances problem solving and proper thinking and can thus be termed as an asset. Secondly, it enables a person to have excellent communication skills. It improves language and comprehension abilities by aiding in the analysis of texts. Furthermore, critical thinking leads to self-reflection since we are able to reflect on our values and make proper decisions. With the changing, economic times which is driven by technology and information one needs to be able to effectively deal with these changes. This requires analysis of information thus pushing for intellectual skills, which we have learnt in this course. Since the start of this course, my critical thinking has vastly improved. It has helped me to think rationally and view things from a different perspective. I can now carefully reflect on my principles of reasoning and internalize them therefore, making me apply it in my day-to-day life. I am now in a position to expose fallacies and avoid faulty reasoning. I am able to come up with solutions to problems in a systematic way and prioritize ideas based on their importance. I have also been able to clearly come up with constructive arguments and evaluate them. More so, I am able to break down information into their constituent parts and logically understand the connections, relevance, and importance of these ideas. In the beginning, I was at the stage of unreflective thinker where I was unaware of significant problems in thinking, but so far I have advanced and I am now in the practicing thinker level. I feel I am at this level since I have recognized the need for regular practice in thinking. I am in a better position to solve problems by using the information that I have. However, limited it may be and to further deduce probable

Sunday, February 2, 2020

Understanding the Motives and the Causes of Impulses Into Research Paper

Understanding the Motives and the Causes of Impulses Into International Relationships - Research Paper Example In the process of sharing these common resources and with the self-satisfaction tendency of individuals, there is need to put up mechanism to regulate self-centeredness of each individuals and to ensure that natural human rights – right to liberty, to life and to property – do not conflict with the similar rights for others in the same society. This mechanism is what constitutes politics and when it succeeds in its quest to preserve the natural rights of individuals under it while maintaining peaceful coexistence, then we may say that it is a legitimate political authority. Because the public is vulnerable to perpetuating individual interests, which may infringe into the rights of others, the conception of political legitimacy so that it fulfils its obligations cannot be left to the public. On this account, the legitimate political authority can be entrusted into the hands of philosophers who have the mental ability to conceive the best political order. Legitimacy in po litics qualifies the virtue of political institutions and political decisions on laws and policies. Philosophers are believed possess to the highest understanding of principles of nature and can be trusted to concoct the best political order. The philosophers’ in-depth analysis of concepts can evaluate the validity of claims and general discourse. With the limitation of human beings in terms of thinking and diversity in understanding and conception of ideas, philosophers too face the greatest threat of conceiving illegitimate and unethical political systems.

Saturday, January 25, 2020

Anti-cancer Drug Targeting AFR Receptor

Anti-cancer Drug Targeting AFR Receptor Results 1a 1b Figure 1 Cell viability data based on the use of the XTT assay Two different lung tumor cell lines were tested: one expressing the mutated AFR receptor (blue line) and one that expresses wild-type AFR (orange line). Figure 1a represented AFR lung cancer cell line with Drug X and figure1b represented AFR lung cancer cell line with drug Y. Cells were seeded in wells of a 96 well plate at 3 x 10*4 cells/well before treatment with the drugs at the indicated concentrations for 72 hours (triplicate samples at each concentration). XTT assay reagent was then added to the wells and the absorbance measured at 450 nm. Control wells (no cells) contained medium but no cells. The Cell Proliferation XTT assay is a colorimetric assay for the nonradioactive analysis of cellular proliferation, viability, quantification of cytotoxic and cytostatic compounds like anticancer drugs and pharmaceutical compounds, evaluation of growth-inhibitory antibodies and physiological mediators that able to inhibit cell growth (Sigma-Aldrich, 2016). Sample is adherent or suspension which cultured in 96-well microplates. A fictional receptor (AFR) was targeted by anti-cancer drug to inhibit the mutated AFR function, causing an anti-proliferative effect and even cell death. XTT ((2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide)) assay was used to measure cell viability in the two different lung tumor cell lines, one expressing the mutated AFR receptor (AFR mut) and one that expresses wild-type AFR (AFR wt). Drug Y was observed to hinder cancer cell growth dose dependently (Figure 1). The amount of observed absorbance increases with cell number and incuba tion time for 72hours when a maximum absorbance level is reached. The plot of the XTT assay data should create a curve with a linear part. This area exhibits the highest sensitivity to changes produced by the experimental parameters. Establishing the XTT assay data for treatment of AFR mutated and AFR wild-type lung cancer cell line with drug X from 0nm to 1600nm (Figure 1a), It was illustrated that the cell viability of mutated AFR increased considerably from 1.1 to 1.3 between 0nm and 800nm and then became steady at approximately 1.4 from 800nm to 1600nm. Compared with the wild type of AFR (Figure1a), the trend of the line was similar to the mutated one but the cell viability was first rised from 0.9 to 1.2 between 0nm and 800nm and finally exhibited a loss of linearity when greater than 800nm. The lung cancer cell line with drug X represented a cell proliferation assay because the absorbance values of the mutated one were greater than control conditions, representing an increase in cell proliferation and viability. On the other hand, investigating the XTT assay data for treatment of AFR mutated and AFR wild-type lung cancer cell line with drug Y from 0nm to 1600nm, It was indicated that the cell viability of m utated AFR started off at about 1.1 from 0nm to 50nm and then occurred a dramatic drop from 1.1 to 0.1 between 50nm to 400nm and finally lied on 0.03 at 1600nm (Figure1b). Compared with the wild type of AFR (Figure1b), the line was also decreasing but showed a completely different trend. The cell viability decreased from 0.89 to 0.88 between 0nm and 800nm stably and then exhibited a significant drop when greater than 800nm and finally lied on 0.8 of 1600nm. The lung cancer cell line with drug Y represented a cell apoptosis assay as the absorbance values were lower than control conditions, showing a decrease in cell proliferation and resulted from cellular necrosis or apoptosis. From the data analysis, drug Y was successfully tested to inhibit the function of mutated AFR which have an anti-proliferative effect to cause cell death and drug Y could be put forward for further testing. Figure 2 Flow cytometry apoptosis data: Annexin V -FITC (x axis) and propidium iodide (Y axis)   Ã‚   The proapoptotic effect of drug X and Y. The AFRmut cell line was treated with each drug at a concentration of 800 nM for 24 hours. The cells were harvested, resuspended in buffer and then treated with Annexin V-FITC and propidium iodide. Cytograms of annexin-V-FITC binding against PI uptake show three populations: (i) viable cells (low FITC and low PI signal) in gate Lower Left; (ii) early apoptotic cells (high FITC and low PI signal) in gate Lower Right and (iii) cells that lost membrane integrity which results in late apoptosis (high FITC and high PI signal) in gate Upper Right. The percentage of cell death increases in the tumor cancer cell line of drug Y, as demonstrated by incorporation of Annexin V. The inhibition of cell proliferation caused by AFRmut was related to the apoptosis induction. Apoptosis is programmed as cell death which is important in development, in normal function of certain tissues and in the response to the damage. Apoptosis involves events which results in the destruction of cell. Annexin V -FITC is a protein that binds to phosphotidylserine which can be labelled and used to detect apoptotic cells. The flow cytometry apoptosis data was plotted on a dot plot and the lower left was represented the viable cells while the upper right and the lower right were represented the dead cells and the apoptotic cells respectively. From the apoptosis data (Figure2), it was observed that the untreated condition showed 77% viable cells and 21% of apoptotic effect. When AFRmut was treated with drug X, the viable cells were increased by 19% and the apoptotic effect was largely decreased to 3%. In contrast, the incorporation with drug Y lead to considerable anti-proliferative effect where 58% of apoptotic cells were observed and viable cells only remained as 40%. Related to the induction of programmed cell death, the majority of cells from the two tumor cell lines were alive upon carrier treatment, the use of AFRmut lead to the entrance of these cells into apoptosis with incorporation of Annexin V. The treatment of drug Y showed a significant apoptotic effect than the drug X, which has a potential to inhibit the function of mutated AFR and results in anti-proliferative effect. Figure 3 Flow cytometry cell cycle data: x-axis shows propidium iodide fluorescence and y-axis shows the number of cells The AFRmut cell line was treated with drug X and Y at a concentration of 800 nM for 24 hours and then fixed with ethanol and stained with propidium iodide before analysis in a flow cytometer. Treating with drug Y showed no cells in G2/M phase. The inhibition of cell proliferation induced by AFRmut was correlated with cell cycle which was evaluated with propidium iodide by flow cytometry. Cell cycle demonstrated the cell progression through a division cycle which result in cell growth and separation into two daughter cells. Live cell observation of cellular DNA and distribution of cell cycle are valuable to regulate apoptosis, and also the tumor behavior and suppressor gene systems. Cells would be distributed into three phases of cell cycle: G0 /G1 phase (2N), S phase (DNA synthesis with various DNA), and G2 /M phase (4N) to identify apoptotic cells with partial DNA content desirably   (Krishnakumar R, Kraus W ,2010). Propidium iodide fluorescence was needed in these actions to bind DNA. From the flow cytometry results by histogram (figure 3), the untreated condition showed 42% of cells in G0/G1 phase while 31% in S phase and 27% in G2/M phase. When the AFRmut was treated with drug X, the cell number in G1 phase dropped by 7% while there was increase of 6% in S Phase. DNA replication occurs more effectively during S phase. Tumor cells with a higher proportion of cells in S phase as tumors were growed faster and more aggressive in that phase so drug X induced proliferation of mutated AFR. However, the addition of drug Y caused effective anti-proliferation effect by increasing the cell numbers in G1 phase from 42% to 86% since the cell has left the cycle and has stopped dividing. There was increase in the cell numbers and grow in size. The decrease from 31% to 14% for S phase indicated the ineffective DNA replication. Moreover, there was no cells observed in G2/M phase when treated with drug Y which represented the increasing numbers of apoptotic cells and the G2/M pha se arrest, which failed the mitosis progression. Discussion Drug Y can be an effective anticancer drug which targets mutated AFR and inhibit its function to lead an anti-proliferative effect. In the present study, two lung tumor cell lines, mutated AFR receptor (AFRmut) and wild-type AFR (AFRwt), Drug Y was found that it could inhibit the growth of the AFR in vitro. The IC50 values of AFRmut and AFRwt were with the same range of 450nm. Additionally, the cell cycle revealed that Drug Y arrested mutated AFR at S phase and G2/M phase. Furthermore, the data demonstrated that Drug Y induced apoptosis in the mechanism assessed by 3 different methods: cell viability assay, apoptosis assay and the cell cycle of flow cytometry. Taken together, these results suggest that the inhibitory effect of Drug Y on cell proliferation in mutated AFR is mediated through induction of cell cycle arrest and apoptotic cell death. The limitation is the flow cytometry are only authorize the relative abundances of cell cycle phases compared to another (Dick FA, Dyson NJ, 2002). These actions can be examined by evaluating a coordinate sample of cells with mitotic inhibitor like nocodazole or G1/S inhibitor like aphidicolin. As these drugs establish a prevalent arrest in M-phase or early S-phase accordingly, moderately proliferating cells will gather at the drug inferred arrest location. For instance, cells arrested in G1 BY pRB expression will stay in G1 phase regardless of nocodazole treatment even regulating cells will accumulate in M-phase[13] Overall, the data demonstrated drug Y is able to develop an anti-cancer drug that targets a receptor called AFR (A Fictional Receptor) to block its activity. Drug Y successfully inhibits the function of mutated AFR by evaluating the cell viability assay, apoptosis assay and the cell cycle of flow cytometry. The assays showed an anti-proliferative effect and even cause cell death, which explains its significant antitumor activity in the various experimental investigations that have assessed. Thus, further studies about the way of administration, dose limiting toxicities and recommended doses are needed for the preclinical development of drug Y to evaluate the potential of the compound as an anticancer drug. References Dick FA, Dyson NJ, 2002. Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins. J. Virol.2;76: 6224-6224. Krishnakumar R, Kraus W, 2010. The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol Cell. 39:8-24 Matthew J., et al, 2012. Analysis of Cell Cycle Position in Mammalian Cells  (59): 3491. Sigma-aldrich, 2016. Cell Proliferation Kit II (XTT) [online] Available at: http://www.sigmaaldrich.com/catalog/product/roche/11465015001?lang=enregion=GB Wang, G., et al, 2005. Antitumor effect of ÃŽÂ ²-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death. Cellular and Molecular Life Sciences CMLS 62.7-8: 881-893.

Friday, January 17, 2020

Effects of electronic gadgets to students studying habits Essay

Abstract Almost all of the students especially high school students are seen of using different kinds of electronic gadgets everyday. Like cellphone, iPad, psp, etc. With that case, students who are addicted in using electronic gadgets affects their studies. As what I have observed, using of electronic gadgets gives bad effects to almost all of the students. The purpose of doing this study is to *Explain the disadvantages of using electronic gadgets among us students *Determine the positive and negative effects of Electronic gadget to students *Show the consequences of excessive use of Electronic gadgets to students *Give the students an advice on how to control their use of electronic gadget. To accomplish this study, I researched for some information that can help me to prove the content of my study. And to be able to solve this problem, I researched for some solutions that can help me to solve this kind of situation, which may also help me to show the goal of my study to my co-students who are addicted in using electronic gadgets. In that way, I can help to prevent the addiction of every student from electronic gadgets. Effects of electronic gadgets 3 EFFECTS OF ELECTRONIC GADGETS TO STUDENTS STUDYING HABITS â€Å"Modern technologies like television and computers provide identifiable educational advantages, such as greater access to information and more compelling presentations of that information. Over-use of technology, though, especially such gadgets as cell phones, iPods and video games.

Thursday, January 9, 2020

Army Strategic Planning Guidance - Free Essay Example

Sample details Pages: 4 Words: 1061 Downloads: 5 Date added: 2019/10/10 Did you like this example? Introduction The chief purpose of specialized Explosive Ordinance Disposal (EOD) force is executed missions within the United States and all over the world in combating military weapons that can cause mass destruction of property as well as the lives of people. The force is committed to protect and maintain peace in the United States and globally at a large by limiting the supply of weapons that can endanger the lives of the public in case the weapons land on the hands of the wrong people. Based on the available Army strategic priorities; I would highly recommend for an Army that has the ability to change and cope with the challenging situations they are facing in their military duties. This is the only priority among the five strategic priorities that appreciates change is inevitable and for that reason, the future holds a lot of uncertainties and therefore the Army should strive to be ready to operate efficiently under circumstances of uncertainties. The defense forces should be prudent in predicting the new emerging threats the Nation is likely to face and for that reason formulate mitigation measures to curb the attack before it occurs. The world has become a complex environment due to increased production of weapons that endanger the lives of people and animals[footnoteRef:2]. That means developing an Army that is flexible enough to respond effectively to the emerging threats to security matters should be the top priority in order to achieve peace and harmony in t he United States and therefore the other strategic goals will thrive well in presence of peace and harmony. Dynamic army force will enable the leaders to make the critical judgment under the unfamiliar conditions which will pave way for other strategic priorities since any unseen obstacle will be easily spotted and effectively counteracted before it results in a significant loss. Don’t waste time! Our writers will create an original "Army Strategic Planning Guidance" essay for you Create order The Army Strategic Planning is undertaking a number of measures to enhance the capability of dynamic army force in the advent of changing war tactics. The following are the number of measures that the Army is undertaking in an attempt to successfully adopts this strategy. First, reforms are being made in Army profession in the 21st century. This is evident through, retaining the gains of the previous decades and also eliminating the harmful leadership and the negative effects of long experienced war Army leaders who depicted professional leadership and skills are been retained in order to disseminate the same values and skills to the current Army in order to facilitate accurate and critical judgment making the ability to under challenging times of uncertainties. Secondly, a lot of learning programmes are been established to educate the leaders for an uncertain future. The endeavor is undertaken in conjunction with other multinational and inter-agency groups. Lastly, leaders are being developed who are competent enough in Cyberspace. The leaders are expected to understand and be swift enough to adapt to constantly volatile capabilities and risks. It is highly stressed that while recruiting, educating training and retaining cyberspace personnel in the entire Army, it will be very crucial to create a strong Army where the force will have a great deep of expertise in cyberspace as well as cyber-electromagnetic activities. Developing persevering soldiers, dynamic leaders, and united army force guided by the code of ethics outlined under the army force code of regulations that will ensure successful accomplishment of different kinds of missions under unfamiliar conditions and changing environments. This is the required capability that needs to be given the highest priority for the Army to operate efficiently and in a complex world. A lot of efforts are needed to support the mentioned strategy by the Army because the strategy demands a collaborative effort across the established Armed forces. Secondly, future Army force has to formulate training programmes that will equip the Army personnel with the right skills and knowledge that will enable the Army to remain resilient under challenging times and endeavor to accomplish the set mission. In addition to that, efforts should be put in place in order to enlighten how forces and those that hold Army leadership positions combine the military resources across war-fighting activities an attempt to achieve the set mission. There are several improved capabilities that the Army can develop as part addressing the capability that can be used by the Army. The following is one of the improved capabilities that the Army should develop in an attempt of curbing the hurdles confronting the discharge of their duties. The institution should consider optimizing human performance as well as ensuring the each soldier is assigned to the right assignment at the correct time consequently maximizing the possibility of accomplishing the mission as per the planned schedule. Institutional as well as operational Army should endeavor to develop creative leaders and increase their performance which will enhance the success of the missions that the Army will undertake. Creative leaders can be developed through subjecting trainee on repetitive training programmes joined with self-study, thorough and careful education all geared at developing innovative leaders that will be resilient and effective in challenging times. Leaders ar e known to impart trust among their fellow leaders and soldiers. Additionally, they develop a spirit of togetherness that fuels the urge of taking the initiative that conforms to the goal of targeting to achieve the mission despite the obstacles that might hinder the success of accomplishing the mission[footnoteRef:3]. Leaders along with Soldiers are accountable to each other and the code of ethics set that demands soldiers to remain persevering and maintain moral character as they perform Army duties. Finally, the implications of potential non-material solution approach recommendations aim at evaluating how it analysis the military combats with emphasize an action warfare and joined air ground activities that aim at evaluating whether there is better an optimal way that can solve a current capability gap. The first implication is that the training analysis evaluates how the Army forces are strategized to fight, groups, air wings task forces and other army groups that are playing a crucial role in contributing to the accomplishment of the mission planned. Secondly, the material analysis explores the entire required equipment and systems that are vital to the forces to facilitate effective execution of the set mission and if new systems are required to meet the existing gap. Next, the leadership and education is the key component that needs to address.

Wednesday, January 1, 2020

What Is Narrative Poetry Definition and Examples

Narrative poetry tells stories through verse. Like a novel or a short story, a narrative poem has plot, characters, and setting. Using a range of poetic techniques such as rhyme and meter, narrative poetry presents a series of events, often including action and dialogue. In most cases, narrative poems have only one speaker—the narrator—who relates the entire story from beginning to end. For example, Edgar Allan Poes The Raven is narrated by a grieving man who, over the course of 18 stanzas, describes his mysterious confrontation with a raven and his descent into despair. Key Takeaways: Narrative Poetry Narrative poetry presents a series of events through action and dialogue.Most narrative poems feature a single speaker: the narrator.Traditional forms of narrative poetry include epics, ballads, and Arthurian romances. Origins of Narrative Poetry The earliest poetry was not written but spoken, recited, chanted, or sung. Poetic devices like rhythm, rhyme, and repetition made stories easier to memorize so they could be transported long distances and handed down through generations. Narrative poetry evolved from this oral tradition. In nearly every part of the world, narrative poetry established a foundation for other literary forms. For example, among the highest achievements of ancient Greece are The Iliad and  The Odyssey, which have inspired artists and writers for more than 2,000 years. Narrative poetry became an enduring literary tradition throughout the Western world. Composed in Old French, Chansons de geste (songs of deeds) stimulated literary activity in medieval Europe. The German saga now known as the Nibelungenlied lives on in Richard Wagners lavish opera series, The Ring of the Nibelung (Der Ring des Nibelungen). The Anglo Saxon narrative Beowulf has inspired modern-day books, movies, operas, and even computer games. In the East, India produced two monumental Sanskrit narratives. The Mahabharata is the worlds longest poem with over 100,000 couplets. The timeless Ramayana spreads Indian culture and ideas across Asia, influencing literature, performance, and architecture. Identifying Narrative Poetry Narrative is one of three major categories of poetry (the other two being dramatic and lyric), and each type of poetry has distinct characteristics and functions. While lyric poems emphasize self-expression, narrative poems emphasize plot. Dramatic poetry, like Shakespeares blank verse plays, is an extended stage production, usually with many different speakers. However, the distinction between genres may blur as poets weave lyrical language into narrative poems. Similarly, a narrative poem might resemble dramatic poetry when the poet incorporates more than one narrator. Therefore, the defining feature of narrative poetry is the narrative arc. From the epic tales of ancient Greece to 21st-century verse novels, the narrator moves through a chronology of events from challenge and conflict to a final resolution. Types of Narrative Poems Ancient and medieval narrative poems were most commonly epics. Written in a grandiose style, these epic narrative poems retold legends of virtuous heroes and powerful gods. Other traditional forms include Arthurian romances about knights and chivalry and ballads about love, heartbreak, and dramatic events. However, narrative poetry is an ever-evolving art, and there are countless other ways to tell stories through verse. The following examples illustrate several different approaches to narrative poetry. Example #1: Henry Wadsworth Longfellow, "The Song of Hiawatha" On  the  Mountains  of  the  Prairie,On  the  great  Red  Pipe-stone  Quarry,Gitche  Manito,  the  mighty,He  the  Master  of  Life,  descending,On  the  red  crags  of  the  quarryStood  erect,  and  called  the  nations,Called  the  tribes  of  men  together. The Song of Hiawatha by American poet Henry Wadsworth Longfellow  (1807–1882) narrates Native American legends in metrical verse that mimics the Finnish national epic, The Kalevala. In turn, The Kalevala echoes early narratives such as The Iliad, Beowulf, and the Nibelungenlied.   Longfellows long poem has all the elements of classical epic poetry: a noble hero, a doomed love, gods, magic, and folklore. Despite its sentimentality and cultural stereotypes, The Song of Hiawatha suggests the haunting rhythms of Native American chants and establishes a uniquely American mythology. Example #2: Alfred, Lord Tennyson, "Idylls of the King" â€Å"I fain would follow love, if that could be;I needs must follow death, who calls for me;Call and I follow, I follow! let me die.† An idyll is a narrative form that originated in ancient Greece, but this idyll is an Arthurian romance based on British legends. In a series of twelve blank verse poems, Alfred, Lord Tennyson (1809–1892) tells the story of King Arthur, his knights, and his tragic love for Guinevere. The book-length work is drawn from medieval writings by Sir Thomas Malory. By writing about chivalry and courtly love, Tennyson allegorized behaviors and attitudes he saw in his own Victorian society. Idylls of the King elevates narrative poetry from story-telling to social commentary. Example #3:  Edna St. Vincent Millay, "The Ballad of the Harp-Weaver" â€Å"Son,† said my mother,  When I was knee-high,  Ã¢â‚¬Å"You’ve need of clothes to cover you,  And not a rag have I.  Ã¢â‚¬Å"There’s nothing in the house  To make a boy breeches,Nor shears to cut a cloth with  Nor thread to take stitches. The Ballad of the Harp-Weaver tells the story of a mothers unconditional love. By the end of the poem, she dies weaving her child magical clothes from her harp. The mothers dialog is quoted by her son, who placidly accepts her sacrifice. American poet Edna St. Vincent Millay (1892–1950) cast the story as a ballad, a form that evolved from traditional folk music. The iambic meter and a predictable rhyme scheme of the poem create a sing-song rhythm that suggests child-like innocence. Famously recited by country musician Johnny Cash, The Ballad of the Harp-Weaver is both sentimental and disturbing. The narrative poem can be understood as a simple story about poverty or a complex commentary on the sacrifices women make to clothe men in the garbs of royalty. In 1923, Edna St. Vincent Millay won a Pulitzer Prize for her poetry collection of the same title. Story song ballads became an important part of the American folk song tradition of the 1960s. Popular examples include Bob Dylans Ballad of a Thin Man and Pete Seegers Waist Deep in the Big Muddy. Example #4: Anne Carson, "Autobiography of Red"   Ã¢â‚¬Å"†¦Small, red, and upright he waited,gripping his new bookbag tightin one hand and touching a lucky penny inside his coat pocket with the other,while the first snows of winterfloated down on his eyelashes and covered the branches around him and silencedall trace of the world.† Canadian poet and translator Anne Carson (b. 1950) loosely based Autobiography of Red on an ancient Greek myth about a heros battle with a red-winged monster. Writing in free verse, Carson recreated the monster as a moody boy who battles modern-day problems related to love and sexual identity. Carsons book-length work belongs to a genre-jumping category known as the verse novel. It shifts between description and dialogue and from poetry to prose as the story moves through layers of meaning. Unlike long verse narratives from antiquity, novels in verse do not adhere to established forms. Russian author Alexander Pushkin (1799–1837) used a complex rhyme scheme and an unconventional meter for his verse novel, Eugene Onegin, and English poet Elizabeth Barrett Browning (1806–1861) composed Aurora Leigh in blank verse. Also writing in blank verse, Robert Browning (1812–1889) composed his novel-length The Ring and the Book from a series of monologues spoken by different narrators. Vivid language and simple stories have made book-length narrative poetry a popular trend in young adult publishing. Jacqueline Woodsons National Book Award-winning Brown Girl Dreaming describes her childhood as an African American growing up in the American South. Other best selling verse novels include The Crossover by Kwame Alexander and the Crank trilogy by Ellen Hopkins. Sources Addison, Catherine. The Verse Novel as Genre: Contradiction or Hybrid? Style. Vol. 43, No. 4 Winter 2009, pp. 539-562. https://www.jstor.org/stable/10.5325/style.43.4.539Carson, Anne. Autobiography of Red.  Random House, Vintage Contemporaries. March 2013.Clark, Kevin. Time, Story, and Lyric in Contemporary Poetry. The Georgia Review. 5 March 2014. https://thegeorgiareview.com/spring-2014/time-story-and-lyric-in-contemporary-poetry-on-the-contemporary-narrative-poem-critical-crosscurrents-edited-by-steven-p-schneider-patricia-smiths-shoulda-been-jimi-savannah-robert-wr/Longfellow, Henry W. The Song of Hiawatha. Maine Historical Society. http://www.hwlongfellow.org/poems_poem.php?pid62Tennyson, Alfred, Lord. Idylls of the King. The Camelot Project.  University of Rochester. https://d.lib.rochester.edu/camelot/publication/idylls-of-the-king-1859-1885